The Truth About High PSA and Prostate Cancer (Top Urologist Explains)

With Dr. Abraham Morgentaler and Dr. Marianne Brandon Listen to the podcast on all of your favorite platforms: Apple: https://podcasts.apple.com/ec/podcast/the-sex-doctors/id1761813985?l=en-GB Spotify: https://open.spotify.com/show/0apSFzquJXKoOGnmI6ndgT?si=e5a1e482c7ca46c7 Find us on: Instagram: https://www.instagram.com/thesexdoctors?utm_source=ig_web_button_share_sheet&igsh=ZDNlZDc0MzIxNw== Facebook: https://www.facebook.com/thesexdoctors YouTube: https://www.youtube.com/@thesexdoctorspod TikTok: https://www.tiktok.com/@thesexdoctor LinkedIn (Dr. Abraham): https://www.linkedin.com/in/abraham-morgentaler-md-81628b6 LinkedIn (Dr. Marianne): https://www.linkedin.com/in/mariannebrandon-59224513 X (Dr. Abraham): https://x.com/DrMorgentaler X (Dr. Marianne): https://x.com/drbrandon In this episode, Dr. Brandon & Dr. Morgentaler talk about what high PSA levels really mean, their relationship to prostate cancer, and why an elevated PSA doesn't necessarily rule out testosterone therapy after proper evaluation. 00:00 PSA Basics Explained — PSA is a normal prostate-produced protein, and an elevated level can signal increased prostate cancer risk without meaning cancer is definitely present. 06:45 What High PSA Really Means — PSA is a probability marker: higher levels raise concern, but prostate cancer can occur at low PSA levels and elevated PSA can occur without cancer. 11:51 MRI vs Biopsy Debate — They discuss how prostate MRI can help determine whether a biopsy is necessary, while noting that a negative MRI can still miss some cancers. 15:57 Prostate Biopsy Evolution — Dr. Morgentaler explains how prostate biopsies progressed from manually guided procedures to more precise ultrasound-guided techniques. 18:25 Pain Control and Safer Biopsies — Improved anesthesia and newer transperineal biopsies can reduce discomfort and lower infection risk compared with traditional transrectal approaches. 22:02 Testosterone with High PSA — An elevated PSA should be properly investigated, but if evaluation shows no evidence of prostate cancer, they argue it should not automatically prevent testosterone therapy. #prostatecancer #testosteronetherapy #PSAlevels